You can train a plug-in effect that has a learning function, for example, a plug-in for noise reduction.
Procedure
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Select an audio range that you want to use for training the plug-in about the noise spectrum. For example, you can use a pause that only contains noise and no dialog.
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In the Direct Offline Processing window, deactivate Auto Apply.
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Add the noise reduction plug-in and activate its learning mode.
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On the Direct Offline Processing window toolbar, activate Audition Loop.
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Activate Audition.
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When you have trained the plug-in, deactivate its learning mode.
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Deactivate Audition.
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Click Discard.
Noise reduction is not applied at this point but the plug-in keeps the parameter settings for the learned noise spectrum.
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Select the whole event.
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In the Direct Offline Processing window, add the noise reduction plug-in and click Apply.
Noise reduction is applied with the current parameter settings.
Result
Noise reduction is applied to the whole event.